Phosphatidylglycerol (PG) by BOC Sciences

Phosphatidylglycerol (PG) is a phospholipid present in lung surfactants. PG is negatively charged due to the polar phosphate group.

BOC Sciences has a specialized liposome technology platform dedicated to providing the most complete solution for liposome drug development services for the pharmaceutical/biotechnology, cosmetic, and nutritional supplement industries. We provide high-quality phosphatidylglycerol.

Definition of Phosphatidylglycerol

The overall molecule is also electronegative. Its basic structure is L-glycerol-3-phosphoric acid backbone with saturated or unsaturated fatty acids connected by ester bonds at the 1 and 2 positions, and glycerol and phosphoric acid form monoesters.

18:0 PG; 1,2-Distearoyl-sn-glycero-3-PG (sodium salt); 1,​2-​Distearoyl-​sn-​glycero-​3-​phospho-​(1′-​rac-​glycerol); 1,2-Distearoyl-sn-glycero-3-phosphoglycerol; 1,2-DSPG

Complete Dissolution of Phosphatidylglycerol

Add a little water to the organic solvent such as methanol or ethanol used, about 0.1%~1% of the total solvent volume (the specific addition amount is subject to the experiment), and then with a high temperature (around the phase transition temperature) water bath ultrasonic to dissolve completely.

Advantages of Phosphatidylglycerol

  • Negative charge on the surface of the particles prevents interparticle aggregation and makes the formulation more stable
  • Negatively charged particles are easier to deliver across membranes

How to Get Phosphatidylglycerol

  • Extraction
  • Chemical synthesis
  • Biosynthesis

Our Advantages

  • Manufacturing process in compliance with GMP requirements
  • High-quality lipid raw materials
  • Strict quality inspection and quality control
  • The most competitive price in the entire network

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